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MCQ on antibacterials: Page-1

Which of the following drugs are chemically NOT compatible

(A) P and S

(C) Q and R

(C) P and R

(C) R and S

Penicillins and aminoglycoside antibiotics are physiologically compatible but not chemically.

Choose the RIGHT statement

(A) The biochemical differences for chemotherapeutic drugs are qualitative only

(B) The biochemical differences for chemotherapeutic drugs are quantitative only

(C) Trimethoprim and pyrimethamine are qualitatively different

(D) Trimethoprim and pyrimethamine are quantitatively different

Drugs act by same mechanism but show different selectivity in their spectrum of activity are called as quantitatively different. Their selectivity depends on the relative dose used. For example, drugs like trimethoprim, pyrimethamine and methotrexate all act by inhibition of dihydrofolate reductase

Co-trimoxazole is a combination of

(A) R and S

(B) P and Q

(C) Q and R

(C) P and S

Choose the WRONG combination of drug and mechanism of action

(A) Rifampicin, DNA polymerase 

(C) Bleomycin, fragmentation of DNA

(C) Mitomycin, alkylating agent  

(C) Dactinomycin, RNA polymerase

One of the drug that is indicated for ulcerative colitis is

(A) Sulfamthoxazole

(B) Sulfadiazine

(C) Mafenide

(C) Sulfasalazine