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MCQ on HPLC: Page-3

Reverse phase column contains
C12 columns

(A) P

(B) Q

(C) R

(D) S

Which of the following HPLC detectors are more sensitive

(A) Bulk property detectors

(B) Solute property detectors

(C) It depends on nature of elute

(D) Some of the bulk property detectors are more sensitive and some of solute property detectors are more sensitive

Amines can be detected by derivitization with

(A) 1-Dimethylaminonaphthalene-5-sulfonyl chloride

(B) 4-Nitrobenzyloxamine chloride

(A) 4-Bromomethyl-7-methoxycoumarin

(D) O-4-Nitrobenzyl- N,N′-diisopropylisourea

The adsorption mechanism of silica gel involves

(A) Interaction of solute with acidic silanol groups

(B) Interaction of solute with basic silanol groups

(C) Interaction of solute with neutral silanol groups

(D) Interaction of solute with inert silane groups

Derivitization of silanol groups in stationary phases can be done by

(A) Trimethyl chloro silane

(B) Dimethyl trichlorosilane

(C) Dialkyll chlorosilane

(D) Tri methyl dichloro silane