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MCQ on antibacterials: Page-2

Identify one of the drug that doesn’t interfere with protein synthesis in bacteria
clarithromycin

(A) S

(B) Q

(C) P,R

(C) Q,S

Moxifloxacin is a fluoroquinolone acts by inhibition of topoisomerase II.

Choose the RIGHT combination of drug and main side effect
drug side effect

(A) P-ii, Q-iii, R-i, S-iv

(B) P-iii, Q-ii, R-iv, S-i

(C) P-iv, Q-i, R-iii, S-ii

(D) P-ii, Q-iv, R-i, S-iii

Sulfonamides produce haemolytic anaemia. Ciprofloxacin produces vestibular disorders. Black water fever is produced by quinine, an antimalarial agent. Amikacin is an aminoglycoside antibiotic that produces ototoxicity and nephrotoxicity.

Choose the WRONG combination of drug and main side effect

(A) Cisplatin, nausea and vomiting 

(B) Trimethoprim. Megaloblastic anaemia

(C) Chloramphenicol, grey baby syndrome

(C) Cefalosporins, ototoxicity

ototoxicity is produced by aminoglycosides. Cefalosporins produce allergic reactions like penicillins.

Which of the following drug’s action is decreased by sodium bicarbonate

(A) Amoxicillin

(B) Methenamine

(C) Ciprofloxacin

(D) Vancomycin

Grey baby syndrome is associated with

(A) Chloramphenicol

(B) Gentamycin

(C) Tetracycline

(D) Ciprofloxacin

Chloramphenicol inhibits ATP synthesis in host resulting in bone marrow depression which can lead to cyanosis. In neonates, the drug is accumulated as there is insufficient development of conjugation and excretion leading to pronounced cyanosis and grey discoloration of the baby.